The lin52 protein is a core component of the dimerization partner, retinoblastoma-like, e2f4, and muvb (dream) complex, which functions as a transcription factor complex to repress cell cycle-dependent...[+]

The lin52 protein is a core component of the dimerization partner, retinoblastoma-like, e2f4, and muvb (dream) complex, which functions as a transcription factor complex to repress cell cycle-dependent gene expression. it localizes to the nucleus. this protein is involved in regulating cell proliferation and is expressed in various tissues during development, including the developing eye, brain, spinal cord, and branchial arches. its function is associated with the formation of germ layers and other embryonic structures. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD