The commd3 protein is a copper metabolism mURR1 domain-containing protein localized to the cytoplasm and nucleus. It functions in copper homeostasis and is involved in the regulation of NF-kappaB signa...[+]

The commd3 protein is a copper metabolism mURR1 domain-containing protein localized to the cytoplasm and nucleus. It functions in copper homeostasis and is involved in the regulation of NF-kappaB signaling. Expression is detected in the brain, eye, neural tube, pronephros, and branchial arches during development. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD