The dppa2 gene encodes a transcription factor containing sap and sap DNA-binding domains. The protein localizes to the nucleus where it functions as a chromatin-associated protein involved in DNA bendi...[+]

The dppa2 gene encodes a transcription factor containing sap and sap DNA-binding domains. The protein localizes to the nucleus where it functions as a chromatin-associated protein involved in DNA bending and transcriptional regulation. It is expressed maternally and zygotically, with transcripts detected during blastula, gastrula, and neurula stages, specifically within the neural plate and eye field. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD