The ppp1r18 gene encodes a protein phosphatase 1 regulatory subunit that targets the catalytic subunit of PP1 to specific subcellular locations, including nuclear speckles and the nucleolus. This regul...[+]

The ppp1r18 gene encodes a protein phosphatase 1 regulatory subunit that targets the catalytic subunit of PP1 to specific subcellular locations, including nuclear speckles and the nucleolus. This regulatory protein is expressed in tissues such as the brain, eye, heart, liver, and pronephros during development. It exhibits distinct expression patterns in various anatomical structures like the branchial arches, cranial ganglia, otic vesicle, and notochord. The ppp1r18 protein localizes to both the nucleus and cytoplasm. [-]

MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD