The gene ppard encodes a peroxisome proliferator-activated receptor delta, which is a ligand-modulated transcription factor belonging to the nuclear hormone receptor superfamily; this protein contains ...[+]

The gene ppard encodes a peroxisome proliferator-activated receptor delta, which is a ligand-modulated transcription factor belonging to the nuclear hormone receptor superfamily; this protein contains a DNA-binding domain with two c4-type zinc fingers and a ligand-binding domain. It is localized to the nucleus. Expression is detected in the brain, spinal cord, eye, branchial arches, pronephros, and limb buds during development. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD