Gene fap encodes a fibroblast activation protein alpha, which is a type ii transmembrane serine protease. The protein localizes to the cell membrane and the extracellular space. It is expressed in the ...[+]

Gene fap encodes a fibroblast activation protein alpha, which is a type ii transmembrane serine protease. The protein localizes to the cell membrane and the extracellular space. It is expressed in the developing pronephros and mesonephric kidney, the brain including the telencephalon, diencephalon, midbrain, and hindbrain, the branchial arches, and the notochord. Expression is also detected in the somites, heart, liver, and the digestive tract including the stomach and intestine during development. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD