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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (0)Lit. (0) GO Terms (14)GO (14) Nucleotides (66)Nucl. (66) Proteins (40)Prot. (40) Interactants (4)Interact. (4) Wiki
XB-GENEPAGE-492814
???displayGene.symbol???:
 sigirr

???displayGene.name???: 
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain

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( Nomenclature history )

???displayGene.geneFunction???
Toll/interleukin receptor and related proteins containing LRR and TIR repeats

AI Protein Function :
sigirr encodes a single‑pass type I membrane receptor of the interleukin‑1 receptor family that acts as a negative regulator of interleukin‑1 and toll‑like receptor signaling, attenuating NF‑κB and MAP...[+]


InterPro :
TIR dom, IL-1 rcpt fam Toll tir struct dom sf, Ig-like dom, [+]

???displayGene.geneInteractants???
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Diseases: 


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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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