The il10rb gene encodes an interleukin-10 receptor subunit which forms a heterodimeric complex with the il10ra chain to constitute a functional receptor for the cytokine il10, mediating jak-stat signal...[+]

The il10rb gene encodes an interleukin-10 receptor subunit which forms a heterodimeric complex with the il10ra chain to constitute a functional receptor for the cytokine il10, mediating jak-stat signaling pathways involved in immune regulation; this protein is membrane-bound and its expression has been documented within lymphoid tissues, myeloid cells, the pronephros, and skin macrophages. [-]

          INFLAMMATORY BOWEL DISEASE 25, AUTOSOMAL RECESSIVE; IBD25

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD