The trim7 gene encodes a tripartite motif-containing protein that functions as an E3 ubiquitin ligase, involved in protein ubiquitination processes. It plays a role in innate immune responses, potentia...[+]

The trim7 gene encodes a tripartite motif-containing protein that functions as an E3 ubiquitin ligase, involved in protein ubiquitination processes. It plays a role in innate immune responses, potentially regulating NF-kB signaling pathways. The protein is expressed in various tissues during development, with specific localization in the cytoplasm. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD