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Summary Expression Phenotypes Gene Literature (15) GO Terms (92) Nucleotides (122) Proteins (59) Interactants (152) Wiki
XB-GENEPAGE-962371
???displayGene.symbol???:
 ldlr

???displayGene.name???: 
low density lipoprotein receptor

???displayGene.synonyms???
fhc , ldlcq2 , ldlr-a , ldlr-b ( Nomenclature history )

???displayGene.geneFunction???
EGF-like calcium ion binding

AI Protein Function :
The ldlr gene encodes a low-density lipoprotein receptor, which is a transmembrane protein localized to the plasma membrane. It functions in cholesterol homeostasis by mediating the endocytosis of lipo...[+]


InterPro :
6-blade b-propeller TolB-like, EGF-like Ca-bd dom, EGF-like dom, EGF-type Asp/Asn hydroxyl site, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
familial hypercholesterolemia

MIM:
HYPERCHOLESTEROLEMIA, FAMILIAL, 1; FHCL1

External Links:
 
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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