The ripor2 gene encodes a protein kinase that functions in the rhoa signaling pathway to regulate cell polarity and movement during gastrulation. It is involved in convergent extension through rock inh...[+]

The ripor2 gene encodes a protein kinase that functions in the rhoa signaling pathway to regulate cell polarity and movement during gastrulation. It is involved in convergent extension through rock inhibition. The protein localizes to the cytoplasm and can associate with the plasma membrane. Expression is detected in the kidney and neural tube. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD