The myom1 gene encodes a structural muscle protein belonging to the myomesin family, which is a core component of the m-line in the sarcomere of skeletal and cardiac muscle. it functions in myofibrillo...[+]

The myom1 gene encodes a structural muscle protein belonging to the myomesin family, which is a core component of the m-line in the sarcomere of skeletal and cardiac muscle. it functions in myofibrillogenesis and provides structural integrity to the sarcomere by cross-linking myosin filaments. expression is localized to the cytoplasm of muscle cells and is prominent in the somites during embryogenesis, later becoming specific to skeletal and cardiac muscle tissue. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD