The gene tamalin encodes a scaffold protein that interacts with group 1 metabotropic glutamate receptors (mGluRs) and cytoskeletal elements, facilitating receptor clustering and trafficking at postsyna...[+]

The gene tamalin encodes a scaffold protein that interacts with group 1 metabotropic glutamate receptors (mGluRs) and cytoskeletal elements, facilitating receptor clustering and trafficking at postsynaptic sites. The protein is expressed in the brain, spinal cord, and eye, localizing to the cytoplasm and plasma membrane where it modulates synaptic signaling and plasticity by organizing receptor complexes. [-]

MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD