The gene spon2 encodes an extracellular matrix protein involved in cell adhesion and axon guidance during neural development. In these frogs, the protein is secreted and localizes to the floor plate an...[+]

The gene spon2 encodes an extracellular matrix protein involved in cell adhesion and axon guidance during neural development. In these frogs, the protein is secreted and localizes to the floor plate and notochord, influencing commissural neuron pathfinding within the spinal cord. Expression is also detected in the developing brain, eye, and cranial ganglia. [-]

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