The arrdc2 gene encodes an arrestin domain-containing protein involved in protein ubiquitination and endocytosis. It is expressed during early development stages including blastula, gastrula, neurula, ...[+]

The arrdc2 gene encodes an arrestin domain-containing protein involved in protein ubiquitination and endocytosis. It is expressed during early development stages including blastula, gastrula, neurula, and tailbud, with later expression found in the brain, eye, neural tube, spinal cord, and branchial arches. The protein localizes to the cytoplasm and cell membrane. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD