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Summary Expression Phenotypes Gene Literature (4) GO Terms (93) Nucleotides (165) Proteins (57) Interactants (90) Wiki
XB-GENEPAGE-949876
???displayGene.symbol???:
 ikbkb

???displayGene.name???: 
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta

???displayGene.synonyms???
ikk2 , ikkb , ikk-beta , ikkbeta ( Nomenclature history )

???displayGene.geneFunction???
serine/threonine kinase

AI Protein Function :
The ikbkb gene encodes a kinase that phosphorylates inhibitors of NF-κB, leading to their degradation and activation of the NF-κB signaling pathway. The protein is cytoplasmic. Its expression is detect...[+]


InterPro :
IKBKB SDD, Ser/Thr kinase AS, Kinase-like dom sf, Prot kinase dom, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
immunodeficiency 15B

MIM:
IMMUNODEFICIENCY 15B; IMD15B

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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