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Summary Expression Expr. PhenotypesPheno. Gene Literature (2)Lit. (2) GO Terms (18)GO (18) Nucleotides (1031)Nucl. (1031) Proteins (39)Prot. (39) Interactants (158)Interact. (158) Wiki
XB-GENEPAGE-955501
???displayGene.symbol???:
 fthi

???displayGene.name???: 
ferritin heavy chain 1

???displayGene.synonyms???
FHC , FTH , FTHL6 , ftmt , HFE5 , NBIA9 [+] ( Nomenclature history )

???displayGene.geneFunction???
This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues.

AI Protein Function :
ftmt encodes a mitochondrial ferritin that stores iron within mitochondria, contributes to iron homeostasis and protects against oxidative stress. The protein is a non‑secreted iron‑binding protein loc...[+]


InterPro :
Ferritin-like diiron, Ferritin CS, Ferritin DPS dom, Ferritin-like, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
hemochromatosis type 5

MIM:
HEMOCHROMATOSIS, TYPE 5; HFE5

External Links:
1/3
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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