Gpbar1 encodes a g-protein coupled receptor that functions as a membrane-bound receptor for bile acids. The protein is localized to the cell membrane and upon binding its ligands, it can activate downs...[+]

Gpbar1 encodes a g-protein coupled receptor that functions as a membrane-bound receptor for bile acids. The protein is localized to the cell membrane and upon binding its ligands, it can activate downstream signaling pathways involving camp. Expression of gpbar1 mrna is detected in the brain and eye during development. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD