Dev Biol 1993 Nov 01;1601:289-91. doi: 10.1006/dbio.1993.1307.

A decreased number of primordial germ cells and the small numbers and reduced sizes of germinal granules in the periodic albino mutant of Xenopus laevis.

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Light and electron microscopy were used to examine the cause of the small number of primordial germ cells (PGCs) that were unexpectedly found in periodic albino (a(p)/a(p)) tadpoles of Xenopus laevis. The observations revealed that the volumes of germ plasm were not significantly different between a(p)/a(p) and wild-type eggs and that the germ plasm of ap/ap eggs contained a smaller number of germinal granules than are present in wild-type eggs and the granules were also smaller than in the wild-type eggs. It was concluded that the number of PGCs might be primarily determined by the number and size of germinal granules.

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