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Are stretch-sensitive channels in molluscan cells and elsewhere physiological mechanotransducers?
Morris CE.
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Single-channel recordings of dozens of cell types, including invertebrate (molluscan) and vertebrate heart cells, reveal stretch-sensitive ion channels. The physiological roles of these channels are undoubtedly diverse but it is usually assumed that the roles they play are related to the channels' mechanosensitive gating. Whether this assumption is valid remains to be seen. Attempts to connect the single-channel observations with the mechanical aspects of physiological or developmental processes are discussed. In the case of molluscan cells, recent work suggests that their stretch channels have physiological functions unrelated to mechanosensitive gating.
Bear,
Calcium-permeable channels in rat hepatoma cells are activated by extracellular nucleotides.
1991, Pubmed
Bear,
Calcium-permeable channels in rat hepatoma cells are activated by extracellular nucleotides.
1991,
Pubmed Bear,
A nonselective cation channel in rat liver cells is activated by membrane stretch.
1990,
Pubmed Bédard,
Channels activated by stretch in neurons of a helix snail.
1992,
Pubmed Belardetti,
Neuronal inhibition by the peptide FMRFamide involves opening of S K+ channels.
,
Pubmed Belardetti,
The growth cones of Aplysia sensory neurons: Modulation by serotonin of action potential duration and single potassium channel currents.
1986,
Pubmed Bevan,
Pressure and flow-dependent vascular tone.
1991,
Pubmed Brezden,
The peptide FMRFamide activates a divalent cation-conducting channel in heart muscle cells of the snail Lymnaea stagnalis.
1991,
Pubmed Chamberlin,
Anisosmotic cell volume regulation: a comparative view.
1989,
Pubmed Erxleben,
Stretch-activated current through single ion channels in the abdominal stretch receptor organ of the crayfish.
1989,
Pubmed Falke,
Activity of ion channels during volume regulation by clonal N1E115 neuroblastoma cells.
1989,
Pubmed Filipovic,
A calcium-permeable stretch-activated cation channel in renal proximal tubule.
1991,
Pubmed
,
Xenbase Franco,
Calcium entry through stretch-inactivated ion channels in mdx myotubes.
1990,
Pubmed Gorczyca,
Single-channel K+ currents in Drosophila muscle and their pharmacological block.
1991,
Pubmed Guharay,
Stretch-activated single ion channel currents in tissue-cultured embryonic chick skeletal muscle.
1984,
Pubmed Gustin,
A mechanosensitive ion channel in the yeast plasma membrane.
1988,
Pubmed Hisada,
Hyperpolarization-activated cationic channels in smooth muscle cells are stretch sensitive.
1991,
Pubmed Hudspeth,
How the ear's works work.
1989,
Pubmed Iwasa,
Stretch sensitivity of the lateral wall of the auditory outer hair cell from the guinea pig.
1991,
Pubmed Kater,
Regulation of growth cone behavior by calcium.
1991,
Pubmed Kimelberg,
Swelling-induced changes in electrophysiological properties of cultured astrocytes and oligodendrocytes. II. Whole-cell currents.
1990,
Pubmed Kirber,
Stretch-activated ion channels in smooth muscle: a mechanism for the initiation of stretch-induced contraction.
1988,
Pubmed Lansman,
Single stretch-activated ion channels in vascular endothelial cells as mechanotransducers?
,
Pubmed Martinac,
Pressure-sensitive ion channel in Escherichia coli.
1987,
Pubmed Martinac,
Mechanosensitive ion channels of E. coli activated by amphipaths.
1990,
Pubmed Medina,
Stretch-activated ion channels modulate the resting membrane potential during early embryogenesis.
1988,
Pubmed Medina,
Sensitivity of stretch-activated K+ channels changes during cell-cleavage cycle and may be regulated by cAMP-dependent protein kinase.
1991,
Pubmed Moody,
A nonselective cation channel activated by membrane deformation in oocytes of the ascidian Boltenia villosa.
1989,
Pubmed Morris,
Stretch-inactivated ion channels coexist with stretch-activated ion channels.
1989,
Pubmed Morris,
Failure to elicit neuronal macroscopic mechanosensitive currents anticipated by single-channel studies.
1991,
Pubmed Morris,
Mechanosensitive ion channels.
1990,
Pubmed Pellegrino,
Stretch-activated cation channels with large unitary conductance in leech central neurons.
1990,
Pubmed Piomelli,
Lipoxygenase metabolites of arachidonic acid as second messengers for presynaptic inhibition of Aplysia sensory cells.
,
Pubmed Sachs,
Mechanical transduction in biological systems.
1988,
Pubmed Sigurdson,
Stretch-activated ion channels in growth cones of snail neurons.
1989,
Pubmed Sokabe,
Quantitative video microscopy of patch clamped membranes stress, strain, capacitance, and stretch channel activation.
1991,
Pubmed Sokabe,
The structure and dynamics of patch-clamped membranes: a study using differential interference contrast light microscopy.
1990,
Pubmed Zagotta,
Single-channel analysis of four distinct classes of potassium channels in Drosophila muscle.
1988,
Pubmed Zhou,
A mechanosensitive channel in whole cells and in membrane patches of the fungus Uromyces.
1991,
Pubmed
