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XB-ART-8935
Bioorg Med Chem Lett 2001 May 21;1110:1261-4. doi: 10.1016/s0960-894x(01)00170-6.
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Synthesis of polyamine derivatives having non-hypotensive Ca2 +-permeable AMPA receptor antagonist activity.

Yoneda Y , Kawajiri S , Hasegawa A , Kito F , Katano S , Takano E , Mimura T .


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In order to obtain non-hypotensive and Ca2+-permeable AMPA receptor antagonists, we have synthesized a series of 1,4-bis(4-piperidinylmethyl)diaminobutanes. Compounds 13b, c, f had desirable properties.

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Species referenced: Xenopus
Genes referenced: bag3