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Summary Attributions Wiki
XB-GRNA-29231172
gRNA Name: neurod2 gRNA4
Synonyms: Rnk20
Genomic Target: neurod2

PAM Sequence: CGG
Sequence: 5' CTGAGTTCAGGTCGTGCATG 3'



Genomic Target tropicalis laevis.L laevis.S
Identities 18/20 20/20 20/20
genome
gRNA
 
5' AATGCACGACCTGAACTCCG 3'
    ||||||||||||||||| |
3' GTACGTGCTGGACTTGAGTC 5'
 
5' CATGCACGACCTGAACTCAG 3'
   ||||||||||||||||||||
3' GTACGTGCTGGACTTGAGTC 5'
 
5' CATGCACGACCTGAACTCAG 3'
   ||||||||||||||||||||
3' GTACGTGCTGGACTTGAGTC 5'
    
Genomic Alignments Position Identity Strand Target Genomic Target
laevis 10.1 Chr9_10L:2323453..2323472 20/20 Antisense target neurod2.L
Chr9_10S:2071448..2071467 20/20 Antisense target neurod2.S
tropicalis 10.0 Chr10:10065283..10065302 18/20 Antisense target neurod2
Chr7:45190832..45190851 19/20 Antisense off-target neurog3
Publications
???morpholino.displaySummary.papersFirst??? Knockdown of NeuroD2 leads to seizure-like behaviour, brain neuronal hyperactivity and a leaky blood-brain barrier in a Xenopus laevis tadpole model of DEE75., Genetics 2024     
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