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Summary Attributions Wiki
XB-GRNA-29231748
gRNA Name: ap3b2 gRNA1
Synonyms: ap3b2 sgRNA2, ap3b2.S sgRNA 2, sgRNA2
Genomic Target: ap3b2

Sequence: 5' GTCTTTGATGGGACATAGGAGGG 3'



Genomic Target laevis.S
Identities 23/23
genome
gRNA
 
5' CCCTCCTATGTCCCATCAAAGAC 3'
   |||||||||||||||||||||||
3' GGGAGGATACAGGGTAGTTTCTG 5'
      
Genomic Alignments Position Identity Strand Target Genomic Target
laevis 10.1 Chr1S:173815517..173815539 23/23 Antisense target ap3b2.S
Chr1L:201990353..201990375 22/23 Antisense off-target ap3b1.L
Chr6L:57485416..57485438 19/23 Antisense off-target cck.L
Chr8L:98026612..98026634 19/23 Antisense off-target papln.L
Chr7S:6039525..6039547 19/23 Sense off-target prkg1.S
tropicalis 10.0 Chr7:19281098..19281120 19/23 Sense off-target fgfr2
Chr2:29988649..29988671 19/23 unknown
Publications
???morpholino.displaySummary.papersFirst??? Seizures, increased interhemispheric synchrony, altered brain transcriptomics and a leaky blood-brain barrier result from loss of ap3b2 in a CRISPR tadpole model of DEE48., Front Neurol 2026     
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