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Summary Attributions Wiki
XB-GRNA-29231753
gRNA Name: ap3b2 gRNA2
Synonyms: ap3b2 sgRNA3, ap3b2.S sgRNA 3, sgRNA3
Genomic Target: ap3b2

Sequence: 5' TGGTCGGGATCCATAACATACGG 3'



Genomic Target tropicalis laevis.S
Identities 21/23 23/23
genome
gRNA
 
5' CCTTATGTTATGGATCCAGACCA 3'
   || |||||||||||||| |||||
3' GGCATACAATACCTAGGGCTGGT 5'
 
5' CCGTATGTTATGGATCCCGACCA 3'
   |||||||||||||||||||||||
3' GGCATACAATACCTAGGGCTGGT 5'
     
Genomic Alignments Position Identity Strand Target Genomic Target
laevis 10.1 Chr1S:173878270..173878292 23/23 Antisense target ap3b2.S
Chr1L:202048682..202048704 23/23 Antisense off-target ap3b1.L
Chr7L:91678296..91678318 20/23 unknown
tropicalis 10.0 Chr3:94750192..94750214 21/23 Antisense target ap3b2
Chr1:185577486..185577508 22/23 Antisense off-target ap3b1
Publications
???morpholino.displaySummary.papersFirst??? Seizures, increased interhemispheric synchrony, altered brain transcriptomics and a leaky blood-brain barrier result from loss of ap3b2 in a CRISPR tadpole model of DEE48., Front Neurol 2026     
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