The kiss1 gene encodes a signaling peptide known as kisspeptin. This neuropeptide is involved in regulating hypothalamic gonadotropin-releasing hormone secretion, which influences reproductive processe...[+]

The kiss1 gene encodes a signaling peptide known as kisspeptin. This neuropeptide is involved in regulating hypothalamic gonadotropin-releasing hormone secretion, which influences reproductive processes and the onset of puberty. It is expressed in the brain, primarily within the habenula, preoptic area, and hypothalamus. The protein is secreted and acts through a membrane-bound receptor. [-]

             hypogonadotropic hypogonadism 13 with or without anosmia

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