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Summary Expression Phenotypes Gene Literature (27) GO Terms (111) Nucleotides (243) Proteins (79) Interactants (322) Wiki
XB-GENEPAGE-482710
???displayGene.symbol???:
 mdm2

???displayGene.name???: 
MDM2 proto-oncogene

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double minute-2 , LOC108713153 , xdm-2 , Xdm2 ( Nomenclature history )

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E3 ubiquitin ligase

AI Protein Function :
The mdm2 protein is an E3 ubiquitin ligase that targets p53 for proteasomal degradation, regulating its stability and transcriptional activity during early embryonic development, including in oocytes, ...[+]


InterPro :
Znf RING, Mdm2, Znf RanBP2, SWIB MDM2 dom sf, [+]

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Diseases: 


MIM:
ACCELERATED TUMOR FORMATION, SUSCEPTIBILITY TO; ACTFS

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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