The ache gene encodes acetylcholinesterase, an enzyme which functions to hydrolyze the neurotransmitter acetylcholine at synaptic clefts and neuromuscular junctions, terminating neuronal signaling. Thi...[+]

The ache gene encodes acetylcholinesterase, an enzyme which functions to hydrolyze the neurotransmitter acetylcholine at synaptic clefts and neuromuscular junctions, terminating neuronal signaling. This hydrolase protein is localized to the extracellular space and plasma membrane. It is expressed in the brain, spinal cord, and skeletal muscle. [-]

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