Fig. 6. CD

Smith SJ et al. (2020)

Xla Wt + adprhl1 CRISPR

NF33-39 (in situ)

Anatomical Phenotype
abnormal development of cardiac ventricle abnormal heart morphology

Expression Phenotype
decreased amount actc1.L expression in heart decreased amount adprhl1.L expression in heart mislocalised actc1.L expression in heart mislocalised adprhl1.L expression in heart

Fig.7.A-D,I-L

Smith SJ et al. (2020)

Xla Wt + adprhl1 CRISPR

NF40-42 (immunohistochemistry)

Anatomical Phenotype
abnormal actin cytoskeleton morphology abnormal cardiac myocyte morphology abnormal development of cardiac ventricle abnormal myofibril morphology abnormal sarcomere morphology abnormally localised outflow tract decreased size of the cardiac ventricle

Fig.S15.A-H

Smith SJ et al. (2020)

Xla Wt + adprhl1 CRISPR

NF44 (immunohistochemistry)

Anatomical Phenotype
abnormal cardiac myocyte morphology abnormal heart contraction abnormal heart morphology abnormal myofibril morphology abnormal sarcomere morphology decreased size of the heart

Fig.S15.I-P

Smith SJ et al. (2020)

Xla Wt + adprhl1 CRISPR

NF44 (immunohistochemistry)

Anatomical Phenotype
abnormal myocardium morphology abnormal myofibril morphology abnormally localised actin filament decreased size of the cardiac ventricle

Fig. 3. B

Smith SJ et al. (2020)

Xla Wt + adprhl1 CRISPR

NF44 (microscopy)

Anatomical Phenotype
abnormal heart contraction abnormal heart morphology decreased size of the cardiac ventricle

XB-PHENO-23529

Smith SJ et al. (2020)

Xla Wt + adprhl1 CRISPR

NF44 (microscopy)

Anatomical Phenotype
abnormal heart contraction decreased size of the cardiac ventricle