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XB-PHENO-23225

Xla Wt + Mmu.lef1-Mmu.ctnnb1-GR + DEX, McLin VA et al. (2007)

Experiment + Assay: Xla Wt + Mmu.lef1-Mmu.ctnnb1-GR + DEX + NF35/36 (in situ hybridization)
Background: Xla.Inbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection Tg(Mmu.lef1-Mmu.ctnnb1-GR) ctnnb1.S
ctnnb1.L
 NF stage 6 (32-cell) blastomere D2.1.1
chemical dexamethasone
NF stage 15 embryo
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 35 and 36  
Expression Phenotypes (3):
mislocalised darmin.L expression in endoderm
decreased amount nr1h5.L expression in liver
decreased amount pdx1.L expression in endoderm
Source: Fig.2.A
Article: XB-ART-35992, PubMed