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XB-PHENO-24173

Xla Wt + chd1 MO, Wyatt BH et al. (2021)

Experiment + Assay: Xla Wt + chd1 MO + NF24-25 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection chd1 MO1 chd1 (Xla)
 NF stage 2 (2-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 24 to NF stage 25  
Anatomical Phenotypes: abnormal development of cranial neural crest
Expression Phenotypes (1):
decreased amount tfap2a.L expression in cranial neural crest
Human Disease Associations: orofacial cleft
Source: Fig. 5 h-j
Article: XB-ART-57345, PubMed