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XB-PHENO-27138

Xla Wt + hwa + dkk1, Azbazdar Y and De Robertis EM (2024)

Experiment + Assay: Xla Wt + hwa + dkk1 + NF28 (whole-mount microscopy)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection dkk1 (Xla) dkk1 (Xla)
 NF stage 3 (4-cell) whole organism
mRNA injection hwa (Xla) hwa (Xla)
 NF stage 3 (4-cell) whole organism
Conditions:
Assay Type Assay Stages Antibody
whole-mount microscopy NF stage 28  
Anatomical Phenotypes: abnormal central nervous system , abnormal head , absent tail , absent tail bud , absent trunk , increased width of cement gland , wholly anteriorized embryo
Source: Fig. 5 D
Article: XB-ART-60778, PubMed