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XB-LINE-2369
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Line Name: Xtr.Tg(hhex:trTA;TRE:ΔLL-Cdh1-GFP)Zorn
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| Summary | |
|---|---|
| Synonym: | Cdh1 mutant (ΔLL-Cdh1) |
| Species: | Xenopus tropicalis |
| Background Strain: | Xtr.Nigerian2NXR |
| Paternal Line: | |
| Maternal Line: | |
| Description: | Custom inducible Tg/mutant line generated by the Zorn Lab. The bipartite transgene Tg(hhex:trTA;TRE:ΔLL-Cdh1-GFP) specifically expresses the mutant ΔLL-Cdh1 or a control wild-type (WT)-Cdh1 in the foregut, upon administration of doxycycline (DOX). |
| Phenotype Description: | compared with non-induced and WT-Cdh1 controls, ~ 70% of ΔLL-Cdh1 transgenic embryos may exhibit tracheo-oesophageal fistula phenotype, with a significantly longer segment of the TE septum forming an unseparated epithelial bilayer. |
| Color Morph: | pigmented |
| Breeding Type: | UNKNOWN |
| Lab of Origin: | Zorn |
| Line Type: | Mutant, Transgenic |
| Mutated Gene(s): | cdh1 |
| MTA Required: | No |
| Public: | Yes |
| Catalogue Number: |
| Stock Center | RRID | Generation | Availability | Mutant Details | Information  |
|---|---|---|---|---|---|
| NXR (US) | |||||
| EXRC (Europe) | |||||
| NBRP (Japan) | |||||
| XLRRI (US) | |||||
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