XB-LINE-1467
Line Name: Xla.Tg(WntREs:dEGFP)Vlemx
| Summary |
|
| Synonym: |
Xla.Tg(pbin7LEF-GFP), pbin8LEF-GFP, Wnt Reporter |
| Species: |
Xenopus laevis |
| Background Strain: |
Xla.Inbred
|
| Description: |
Construct contains a synthetic Wnt-responsive promoter consisting of 7 copies of a TCF/LEF1 binding DNA element, a minimal TATA box and a reporter gene encoding destabilized EGFP and a polyA sequence. The transgene is flanked on both sides by two copies of the chicken HS4-core sequence. GFP expression of dynamic patterns of Wnt/Beta-catenin signalling activity. |
| Phenotype Description: |
GFP expression reveals dynamic patterns of Wnt/beta-catenin signaling activity. First clear signals present at neurula stage. |
| Breeding Type: |
OUTBRED
|
| Lab of Origin: |
Vleminckx Lab |
| Line Type: |
Transgenic |
| Mutated Gene(s): |
|
| MTA Required: |
No
|
| Public: |
Yes
|
| Stock Center |
RRID |
Generation |
DOB |
# Males |
# Females |
Availability |
Mutant Details |
| EXRC (Europe) |
EXRC_0065 |
|
| NXR (US) |
NXR_0064 |
F6 |
|
16 |
25 |
Order
|
|
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