XB-LINE-1537
Line Name: Xtr.atp7amZimml
| Summary |
|
| Synonym: |
Kaleidoscope, kalmh18 |
| Species: |
Xenopus tropicalis |
| Background Strain: |
Xtr.Nigerian1EXRC
|
| Description: |
A mutation affecting retinal epithelium identified in the Mill Hill screen for ENU-induced mutations. Splicing mutation in the atp7a copper transporter which results in the deletion of the C-terminal 125 amino acids.Model for Menkes disease. |
| Phenotype Description: |
Retinal epithelium pigmentation is variegated, melanocytes reduced, head cartilage defects. |
| Color Morph: |
pigmented |
| Breeding Type: |
OUTBRED
|
| Lab of Origin: |
Zimmerman Lab |
| Line Type: |
Mutant |
| Mutated Gene(s): |
atp7a
|
| MTA Required: |
Yes
|
| Public: |
Yes
|
|
Xtr.atp7a mutant embryos (also known as kaleidoscope /kal) show variegated retinal pigmentation, decreased melanophore number, and head cartilage defects
|
|
Xtr.atp7a mutant embryos (also known as kaleidoscope /kal) show variegated retinal pigmentation, decreased melanophore number, and head cartilage defects
|
| Stock Center |
RRID |
Generation |
DOB |
# Males |
# Females |
Availability |
Mutant Details |
| EXRC (Europe) |
EXRC_6001 |
|
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