Larger Image Figure 2. Ion selectivity of the rSkM1 Na+ channel. (A) Whole-cell recordings of the rSkM1 Na+ channel in the presence of 96 mM NaCl, LiCl, NH4Cl, and KCl solutions. Oocytes were depolarized between −60 and +50 mV from a holding potential of −120 mV. Currents traces displayed are from −50 to +40 mV in 10-mV increments. Currents were corrected for leak and cell capacity. (B) Current-voltage relationship of the same oocyte shown in A for Na+ (▪), Li+ (○), NH4+ (♦), and K+ (▵). The data were fit to a Boltzmann distribution as described in materials and methods. Image published in: Tsushima RG et al. (1997) Image reproduced on Xenbase with permission of the publisher and the copyright holder. Creative Commons Attribution-NonCommercial-ShareAlike license Permanent Image Page Printer Friendly View XB-IMG-120435 |