Figure 5. Co2+/Ni2+-histone binding site selectivity. (A) Co2+-aspartate coordination within an electronegative patch of H2A. (B) Ni2+ coordination to histidine, glutamate and an additional histidine ligand from the H4 tail of a neighboring particle (gray carbon atoms). (A and B) Co2+/Ni2+ ions and coordinate (-covalent) bonds appear as magenta spheres and lines, respectively. An anomalous difference electron density map, contoured at 4Ï (A) and 8Ï (B), is shown superimposed on the model.
Image published in: Mohideen K et al. (2010)
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