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Figure 11. Model of HCO−3 reabsorption by the renal proximal tubuleBicarbonate appears in the lumen of the proximal tubule as the result of glomerular filtration. Abbreviations: AQP1, aquaporin 1; CAII, carbonic anhydrase II; CAIV, carbonic anhydrase IV; NBCe1-A, renal splice variant of electrogenic Na/HCO3 cotransporter 1; and NHE3, Na+–H+ exchanger 3.

Image published in: Boron WF (2010)

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