Figure 2. Resistance to reprogramming increases as cells differentiate. The extent of resistance to reprogramming (equivalent to a decrease in reprogramming efficiency) as cells differentiate, when tested by nuclear transfer (aâc), cell fusion (heterokaryon) (d) and induced pluripotency (e). Reproduced, with permission, from [15](a), [16](b), [5](c), [19](d) (but also see [100,101]) and [22](e). Abbreviations: ES, embryonic stem; ESRA, retinoic-acid differentiated embryonic stem cells.
Image published in: Pasque V et al. (2011)
© 2011 The Authors. Creative Commons Attribution license
Permanent Image Page
Printer Friendly View
XB-IMG-129293