tubb2b has 68 expression phenotype(s)
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Images Sources Experiment + Assay Phenotypes Human Diseases
Fig. 6, Table 2

Hutlet B and Schlosser G (2025) 		Xla Wt + pias4

NF13-14 (in situ hybridization)
Anatomical Phenotype
decreased size of the preplacodal ectoderm
Expression Phenotype
decreased amount tubb2b.L expression in neuroectoderm
decreased amount eya1.L expression in cranial placode
decreased amount foxd3.L expression in cranial neural crest
decreased amount foxd3.L expression in neuroectoderm
decreased amount neurod1.L expression in neuroectoderm
decreased amount neurog1.L expression in neuroectoderm
decreased amount neurog2.L expression in neuroectoderm
decreased amount six1.L expression in cranial placode
decreased amount sox3.L expression in neural plate
mislocalised sox3.L expression in embryo
mislocalised sox3.L expression in non-neural ectoderm
Fig. 5, Table2

Hutlet B and Schlosser G (2025) 		Xla Wt + pias4 MO

NF13-14 (in situ hybridization)
Anatomical Phenotype
decreased size of the preplacodal ectoderm
Expression Phenotype
decreased amount tubb2b.L expression in neuroectoderm
decreased amount eya1.L expression in cranial placode
decreased amount foxd3.L expression in neuroectoderm
decreased amount neurod1.L expression in cranial placode
decreased amount neurod1.L expression in neuroectoderm
decreased amount neurog1.L expression in neuroectoderm
decreased amount neurog2.L expression in neuroectoderm
decreased amount six1.L expression in cranial placode
increased amount foxd3.L expression in neuroectoderm
increased amount sox3.L expression in non-neural ectoderm
mislocalised sox3.L expression in embryo
Fig. 7, Table 3

Hutlet B and Schlosser G (2025) 		Xla Wt + smarce1 MO

NF13-14 (in situ hybridization)
Expression Phenotype
absent tubb2b.L expression in non-neural ectoderm
decreased amount tubb2b.L expression in neuroectoderm
decreased amount eya1.L expression in preplacodal ectoderm
decreased amount foxd3.L expression in cranial neural crest
decreased amount neurod1.L expression in non-neural ectoderm
decreased amount neurog1.L expression in non-neural ectoderm
decreased amount neurog2.L expression in non-neural ectoderm
decreased amount six1.L expression in preplacodal ectoderm
increased amount sox3.L expression in neural plate
mislocalised sox3.L expression in non-neural ectoderm
Fig. 3 (neurula)

Damuth DL et al. (2024) 		Xla Wt + Xla.sox21.L

NF15 (RT-PCR)
Expression Phenotype
decreased amount tubb2b.L expression in neuron
decreased amount sox2.L expression in neural stem cell
Fig. 3 (neurula)

Damuth DL et al. (2024) 		Xla Wt + Xla.sox21.S

NF15 (RT-PCR)
Expression Phenotype
decreased amount tubb2b.L expression in neuron
decreased amount sox2.L expression in neural stem cell
increased amount myt1.L expression in neural stem cell
increased amount neurod1.L expression in neural progenitor cell
increased amount six1.L expression in preplacodal ectoderm
Fig. 2E r1c2, r2c2

Wong S et al. (2023) 		Xla Wt + Hsa.RAF1

NF28 (in situ hybridization)
Anatomical Phenotype
abnormal spinal cord morphology
duplicated tail
Expression Phenotype
mislocalised tubb2b.L expression in ventral side
increased amount tbxt.L expression in anterior neural tube
mislocalised tbxt.L expression in chordoneural hinge
mislocalised tbxt.L expression in tail tip
Fig. S3 r2c5-8

Job F et al. (2023) 		Xla Wt + otud3 MO1/2

NF35/36 (in situ hybridization)
Anatomical Phenotype
abnormal eye morphology
abnormal head morphology
Expression Phenotype
mislocalised tubb2b.L expression in forebrain
Fig. 4 FGH

Virgirinia RP et al. (2021) 		Xtr Wt + clk3 MO

NF37/38 (qPCR)
Expression Phenotype
decreased amount tubb2b expression in whole organism
decreased amount ncam1 expression in whole organism
Fig. 2 B

Marquez J et al. (2021) 		Xtr wt+ nup205 MO

NF 28
Anatomical Phenotype
abnormally decreased number of cilium in the mucociliary epithelium
abnormal multiciliated epidermal cell
Expression Phenotype
decreased amount tubb2b expression in multiciliated epidermal cell
ciliopathy
Fig.6.S1.E

Chen M et al. (2020) 		Xla Wt + tmem79 MO

NF16 (in situ hybridization)
Expression Phenotype
decreased amount tubb2b.L expression in neural plate
decreased amount tubb2b.L expression in Rohon-Beard neuron
decreased amount tubb2b.L expression in trigeminal placode
decreased amount ag1.L expression in anterior neural ridge
decreased amount ag1.L expression in cement gland primordium
decreased amount egr2.L expression in rhombomere R3
decreased amount egr2.L expression in rhombomere R5
decreased amount en2.L expression in presumptive midbrain-hindbrain boundary
decreased amount foxg1.L expression in anterior neural ridge